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Literature summary extracted from

  • Huang, H.; Chang, W.C.; Pai, P.J.; Romo, A.; Mansoorabadi, S.O.; Russell, D.H.; Liu, H.W.
    Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues (2012), J. Am. Chem. Soc., 134, 16171-16174.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.1.23 [(2R)-2-hydroxy-2-(2-methylidenecyclopropyl)ethyl]phosphonate
-
 Streptomyces wedmorensis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.23 Iron a mononuclear iron enzyme Streptomyces wedmorensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.23 (R)-2-hydroxypropylphosphonic acid + H2O2 Streptomyces wedmorensis
-
 2-oxo-propylphosphonic acid + H2O
-
 ?
1.11.1.23 (S)-2-hydroxypropylphosphonate + H2O2 Streptomyces wedmorensis
-
 (1R,2S)-1,2-epoxypropylphosphonate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.23 Streptomyces wedmorensis Q56185
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.23 (2-cyclopropyl-2-oxoethyl)phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?
1.11.1.23 (3-cyclopropyloxiran-2-yl)phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?
1.11.1.23 (R)-2-hydroxypropylphosphonic acid + H2O2
-
 Streptomyces wedmorensis 2-oxo-propylphosphonic acid + H2O
-
 ?
1.11.1.23 (S)-2-hydroxypropylphosphonate + H2O2
-
 Streptomyces wedmorensis (1R,2S)-1,2-epoxypropylphosphonate + H2O
-
 ?
1.11.1.23 [(2R)-2-cyclopropyl-2-hydroxyethyl]phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?
1.11.1.23 [(2S)-2-cyclopropyl-2-hydroxyethyl]phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?
1.11.1.23 [(2S)-2-hydroxy-2-(2-methylidenecyclopropyl)ethyl]phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?
1.11.1.23 [3-(2-methylidenecyclopropyl)oxiran-2-yl]phosphonate + H2O2
-
 Streptomyces wedmorensis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.23 HppE
-
 Streptomyces wedmorensis