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Literature summary extracted from

  • Milaczewska, A.; Broclawik, E.; Borowski, T.
    On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study (2013), Chemistry, 19, 771-781.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.23 Fe2+ required Streptomyces wedmorensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.23 (R)-2-hydroxypropylphosphonate + H2O2 Streptomyces wedmorensis
-
 2-oxopropylphosphonic acid + H2O
-
 ?
1.11.1.23 (S)-2-hydroxypropylphosphonate + H2O2 Streptomyces wedmorensis
-
 (1R,2S)-1,2-epoxypropylphosphonate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.23 Streptomyces wedmorensis Q56185
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.23 (R)-2-hydroxypropylphosphonate + H2O2
-
 Streptomyces wedmorensis 2-oxopropylphosphonic acid + H2O
-
 ?
1.11.1.23 (S)-2-hydroxypropylphosphonate + H2O2
-
 Streptomyces wedmorensis (1R,2S)-1,2-epoxypropylphosphonate + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.23 (S)-2-hydroxypropylphosphonic acid epoxidase
-
 Streptomyces wedmorensis
1.11.1.23 HppE
-
 Streptomyces wedmorensis

Cofactor

EC Number Cofactor Comment Organism Structure
1.11.1.23 FMN
-
 Streptomyces wedmorensis
1.11.1.23 NAD(P)H
-
 Streptomyces wedmorensis