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Literature summary extracted from
- beta,beta-carotene 15,15'-monooxygenase and its substrate beta-carotene modulate migration and invasion in colorectal carcinoma cells (2013), Am. J. Clin. Nutr., 98, 413-422.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.13.11.63 | quantitative reverse-transcriptase PCR enzyme expression analysis | Homo sapiens |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.13.11.63 | additional information | LoVo cells are transfected with either BCMO1 siRNA or scrambled siRNA. BCMO1 siRNA knockdown increases migration and invasion in LoVo cells and increased the expression of MMP7 and MMP28 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.63 | beta-carotene + O2 | Mus musculus | - |
2 all-trans-retinal | - |
? |  |
| 1.13.11.63 | beta-carotene + O2 | Homo sapiens | - |
2 all-trans-retinal | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.11.63 | Homo sapiens | Q9HAY6 | gene Bcmo1 | - |
| 1.13.11.63 | Mus musculus | Q9JJS6 | gene Bcmo1 | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.13.11.63 | colonic cancer cell | - |
Homo sapiens | - |
| 1.13.11.63 | colorectal cancer cell | - |
Mus musculus | - |
| 1.13.11.63 | LoVo cell | - |
Homo sapiens | - |
| 1.13.11.63 | additional information | quantitative reverse-transcriptase PCR enzyme expression analysis | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.63 | beta-carotene + O2 | - |
Mus musculus | 2 all-trans-retinal | - |
? | |
| 1.13.11.63 | beta-carotene + O2 | - |
Homo sapiens | 2 all-trans-retinal | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.13.11.63 | Bcmo1 | - |
Mus musculus |
| 1.13.11.63 | Bcmo1 | - |
Homo sapiens |
| 1.13.11.63 | beta,beta-carotene 15,15'-monooxygenase | - |
Mus musculus |
| 1.13.11.63 | beta,beta-carotene 15,15'-monooxygenase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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