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Literature summary extracted from

  • Wischang, D.; Hartung, J.
    Bromination of phenols in bromoperoxidase-catalyzed oxidations (2012), Tetrahedron, 68, 9456-9463.
No PubMed abstract available

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.18 vanadate in the solid state structure, every protein monomer binds one vanadate to the tele imidazole nitrogen of residue His486. In solutions of sodium orthovanadate, isoform apobromoperoxidase II recovers bromoperoxidase activity by one order of magnitude faster than apobromoperoxidase I Ascophyllum nodosum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.18 67400
-
 2 * 67400, calculated, 2 * 64200-65000, MALDI-TOF Ascophyllum nodosum
1.11.1.18 127700 130000 MALDI-TOF Ascophyllum nodosum
1.11.1.18 136000
-
 gel filtration Ascophyllum nodosum

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.18 Ascophyllum nodosum P81701 isoform VBrPO(AnI)
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.18 Br- + H2O2 + 2-methoxyphenol
-
 Ascophyllum nodosum 2-bromo-6-methoxyphenol + 4-bromo-6-methoxyphenol + H2O 56% of product, in a 21/79 mixture of o-/p-regioisomers, plus 10% 2,4-dibromo-6-methoxyphenol ?
1.11.1.18 Br- + H2O2 + 2-methylphenol
-
 Ascophyllum nodosum 2-bromo-6-methylphenol + 4-bromo-6-methylphenol + H2O 68% of product, in a 16/84 mixture of o-/p-regioisomers, plus 4% 2,4-dibromophenol ?
1.11.1.18 Br- + H2O2 + 2-t-butylphenol
-
 Ascophyllum nodosum 2-bromo-6-t-butylphenol + 4-bromo-6-t-butylphenol + H2O 42% of product, in a 36/64 mixture of o-/p-regioisomers, plus 2% 2,4-dibromo-6-t-butylphenol ?
1.11.1.18 Br- + H2O2 + phenol
-
 Ascophyllum nodosum 2-bromophenol + 4-bromophenol + H2O 69% of product, in a 91/9 mixture of o-/p-regioisomers, plus 3% 2,4-dibromo-6-methylphenol and some 2,4,6-tribromophenol ?
1.11.1.18 additional information enzyme uses hydrogen peroxide and bromide yielding molecular bromine as reagent for electrophilic hydrocarbon bromination Ascophyllum nodosum ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.18 dimer 2 * 67400, calculated, 2 * 64200-65000, MALDI-TOF Ascophyllum nodosum

Synonyms

EC Number Synonyms Comment Organism
1.11.1.18 apobromoperoxidase I
-
 Ascophyllum nodosum
1.11.1.18 VBrPO(AnI)
-
 Ascophyllum nodosum