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Literature summary extracted from

  • Li, C.W.; Lee, S.H.; Chieh, P.S.; Lin, C.S.; Wang, Y.C.; Chan, M.T.
    Arabidopsis root-abundant cytosolic methionine sulfoxide reductase B genes MsrB7 and MsrB8 are involved in tolerance to oxidative stress (2012), Plant Cell Physiol., 53, 1707-1719.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.4.12 cytosol
-
 Arabidopsis thaliana 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.4.12 L-methionine (R)-sulfoxide + thioredoxin Arabidopsis thaliana
-
 L-methionine + thioredoxin disulfide + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.12 Arabidopsis thaliana
-
 ecotype Columbia
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.12 flower low expression Arabidopsis thaliana
-
1.8.4.12 leaf low expression Arabidopsis thaliana
-
1.8.4.12 root highest expression in roots Arabidopsis thaliana
-
1.8.4.12 stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.12 L-methionine (R)-sulfoxide + thioredoxin
-
 Arabidopsis thaliana L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.12 methionine sulfoxide reductase B
-
 Arabidopsis thaliana
1.8.4.12 MsrB7 isoform Arabidopsis thaliana
1.8.4.12 MsrB8 isoform Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.4.12 thioredoxin
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
1.8.4.12 Arabidopsis thaliana isoforms MsrB7 and MsrB8 are induced by oxidative stress up

General Information

EC Number General Information Comment Organism
1.8.4.12 malfunction cytosolic MsrB7 and MsrB8 knockdown lines are sensitive to oxidative stress Arabidopsis thaliana
1.8.4.12 physiological function isoforms MsrB7 and MsrB8 play an important role in defense against oxidative stress. Transgenic plants overexpressing MsrB7 or MsrB8 are viable and survive after methyl viologen and H2O2 treatment. Arabidopsis plants overexpressing isoforms MsrB7/B8 have shorter roots Arabidopsis thaliana