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Literature summary extracted from

  • Wagner, L.; Zlabek, V.; Trattner, S.; Zamaratskaia, G.
    In vitro inhibition of 7-ethoxyresorufin-O-deethylase (EROD) and p-nitrophenol hydroxylase (PNPH) activities by sesamin in hepatic microsomes from two fish species (2013), Mol. Biol. Rep., 40, 457-462.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.29 sesamin mechanism-based inhibition with decrease in the IC50 value when 5 min pre-incubation step is included Cyprinus carpio
1.14.13.29 sesamin mechanism-based inhibition with decrease in the IC50 value when 5 min pre-incubation step is included Salmo salar

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.29 microsome
-
 Cyprinus carpio
-
-
1.14.13.29 microsome
-
 Salmo salar
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.29 Cyprinus carpio
-
-
-
1.14.13.29 Salmo salar
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.29 liver
-
 Cyprinus carpio
-
1.14.13.29 liver
-
 Salmo salar
-

Synonyms

EC Number Synonyms Comment Organism
1.14.13.29 PPH
-
 Cyprinus carpio
1.14.13.29 PPH
-
 Salmo salar

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.13.29 0.0152
-
 25°C, pH 7.4, 5 min preincubation in presence of NADPH Salmo salar sesamin
1.14.13.29 0.0207
-
 25°C, pH 7.4, 5 min preincubation in presence of NADPH Cyprinus carpio sesamin
1.14.13.29 0.0617
-
 25°C, pH 7.4 Salmo salar sesamin
1.14.13.29 0.1943
-
 25°C, pH 7.4 Cyprinus carpio sesamin