BRENDA - Enzyme Database

Catalase is inhibited by flavonoids

Krych, J.; Gebicka, L.; Int. J. Biol. Macromol. 58, 148-153 (2013)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.11.1.6
(+)-catechin
-
Bos taurus
1.11.1.6
(-)-epigallocatechin
-
Bos taurus
1.11.1.6
apigenin
-
Bos taurus
1.11.1.6
Astragalin
-
Bos taurus
1.11.1.6
catechol
-
Bos taurus
1.11.1.6
Epicatechin gallate
-
Bos taurus
1.11.1.6
epigallocatechin gallate
-
Bos taurus
1.11.1.6
galangin
-
Bos taurus
1.11.1.6
gallic acid
-
Bos taurus
1.11.1.6
kaempferol
-
Bos taurus
1.11.1.6
luteolin
-
Bos taurus
1.11.1.6
additional information
enzyme inhibition by flavonoids, structure-function relationship, overview
Bos taurus
1.11.1.6
myricetin
-
Bos taurus
1.11.1.6
pyrogallol
-
Bos taurus
1.11.1.6
quercetin
-
Bos taurus
1.11.1.6
rutin
-
Bos taurus
1.11.1.6
Sodium azide
-
Bos taurus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.11.1.6
2 H2O2
Bos taurus
via intermediate Compound I
O2 + 2 H2O
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.11.1.6
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.11.1.6
liver
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.11.1.6
2 H2O2
via intermediate Compound I
725146
Bos taurus
O2 + 2 H2O
-
-
-
?
Temperature Optimum [C]
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
1.11.1.6
23
-
assay at room temperature
Bos taurus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.11.1.6
7
-
assay at
Bos taurus
IC50 Value
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
1.11.1.6
0.000014
-
pH 7.0, 23C
Bos taurus
myricetin
1.11.1.6
0.000029
-
pH 7.0, 23C
Bos taurus
Epicatechin gallate
1.11.1.6
0.00033
-
pH 7.0, 23C
Bos taurus
epigallocatechin gallate
1.11.1.6
0.00122
-
pH 7.0, 23C
Bos taurus
(+)-catechin
1.11.1.6
0.0018
-
pH 7.0, 23C
Bos taurus
pyrogallol
1.11.1.6
0.0116
-
pH 7.0, 23C
Bos taurus
luteolin
1.11.1.6
0.0166
-
pH 7.0, 23C
Bos taurus
apigenin
1.11.1.6
0.02
-
pH 7.0, 23C
Bos taurus
galangin
1.11.1.6
0.033
-
pH 7.0, 23C
Bos taurus
Astragalin
1.11.1.6
0.036
-
pH 7.0, 23C
Bos taurus
rutin
1.11.1.6
0.045
-
pH 7.0, 23C
Bos taurus
quercetin
1.11.1.6
0.046
-
pH 7.0, 23C
Bos taurus
gallic acid
1.11.1.6
0.049
-
pH 7.0, 23C
Bos taurus
(-)-epigallocatechin
1.11.1.6
0.056
-
pH 7.0, 23C
Bos taurus
catechol
1.11.1.6
0.0744
-
pH 7.0, 23C
Bos taurus
kaempferol
1.11.1.6
0.345
-
pH 7.0, 23C
Bos taurus
Sodium azide
IC50 Value (protein specific)
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
1.11.1.6
0.000014
-
pH 7.0, 23C
Bos taurus
myricetin
1.11.1.6
0.000029
-
pH 7.0, 23C
Bos taurus
Epicatechin gallate
1.11.1.6
0.00033
-
pH 7.0, 23C
Bos taurus
epigallocatechin gallate
1.11.1.6
0.00122
-
pH 7.0, 23C
Bos taurus
(+)-catechin
1.11.1.6
0.0018
-
pH 7.0, 23C
Bos taurus
pyrogallol
1.11.1.6
0.0116
-
pH 7.0, 23C
Bos taurus
luteolin
1.11.1.6
0.0166
-
pH 7.0, 23C
Bos taurus
apigenin
1.11.1.6
0.02
-
pH 7.0, 23C
Bos taurus
galangin
1.11.1.6
0.033
-
pH 7.0, 23C
Bos taurus
Astragalin
1.11.1.6
0.036
-
pH 7.0, 23C
Bos taurus
rutin
1.11.1.6
0.045
-
pH 7.0, 23C
Bos taurus
quercetin
1.11.1.6
0.046
-
pH 7.0, 23C
Bos taurus
gallic acid
1.11.1.6
0.049
-
pH 7.0, 23C
Bos taurus
(-)-epigallocatechin
1.11.1.6
0.056
-
pH 7.0, 23C
Bos taurus
catechol
1.11.1.6
0.0744
-
pH 7.0, 23C
Bos taurus
kaempferol
1.11.1.6
0.345
-
pH 7.0, 23C
Bos taurus
Sodium azide
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.11.1.6
(+)-catechin
-
Bos taurus
1.11.1.6
(-)-epigallocatechin
-
Bos taurus
1.11.1.6
apigenin
-
Bos taurus
1.11.1.6
Astragalin
-
Bos taurus
1.11.1.6
catechol
-
Bos taurus
1.11.1.6
Epicatechin gallate
-
Bos taurus
1.11.1.6
epigallocatechin gallate
-
Bos taurus
1.11.1.6
galangin
-
Bos taurus
1.11.1.6
gallic acid
-
Bos taurus
1.11.1.6
kaempferol
-
Bos taurus
1.11.1.6
luteolin
-
Bos taurus
1.11.1.6
additional information
enzyme inhibition by flavonoids, structure-function relationship, overview
Bos taurus
1.11.1.6
myricetin
-
Bos taurus
1.11.1.6
pyrogallol
-
Bos taurus
1.11.1.6
quercetin
-
Bos taurus
1.11.1.6
rutin
-
Bos taurus
1.11.1.6
Sodium azide
-
Bos taurus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.11.1.6
2 H2O2
Bos taurus
via intermediate Compound I
O2 + 2 H2O
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.11.1.6
liver
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.11.1.6
2 H2O2
via intermediate Compound I
725146
Bos taurus
O2 + 2 H2O
-
-
-
?
Temperature Optimum [C] (protein specific)
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
1.11.1.6
23
-
assay at room temperature
Bos taurus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.11.1.6
7
-
assay at
Bos taurus
General Information
EC Number
General Information
Commentary
Organism
1.11.1.6
physiological function
catalases, heme enzymes, which catalyze decomposition of hydrogen peroxide to water and molecular oxygen, belong to the antioxidant defense system of the cell
Bos taurus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
1.11.1.6
physiological function
catalases, heme enzymes, which catalyze decomposition of hydrogen peroxide to water and molecular oxygen, belong to the antioxidant defense system of the cell
Bos taurus