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Literature summary extracted from

  • Kitamura, T.; Naganuma, T.; Abe, K.; Nakahara, K.; Ohno, Y.; Kihara, A.
    Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1 (2013), Biochim. Biophys. Acta, 1831, 1395-1401.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.48 expressed in FAA-K1A cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.48 plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.48 hexadecanal + NAD+ + H2O Homo sapiens high activity hexadecanoic acid + NADH
-
 ?
1.2.1.48 trans-2-hexadecenal + NAD+ + H2O Homo sapiens
-
 trans-2-decenoic acid + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.48 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.2.1.48 palmitoylation
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.48 lung
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.48 hexadecanal + NAD+ + H2O high activity Homo sapiens hexadecanoic acid + NADH
-
 ?
1.2.1.48 trans-2-hexadecenal + NAD+ + H2O
-
 Homo sapiens trans-2-decenoic acid + NADH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.48 Aldh3b1
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.48 NAD+
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
1.2.1.48 malfunction ALDH3B1 does not cause further impairment of the sphingolipid metabolism in the ALDH3A2-deficient cells Homo sapiens
1.2.1.48 metabolism the enzyme is not involved in the long-chain base metabolism Homo sapiens
1.2.1.48 physiological function the likely physiological function of ALDH3B1 is to oxidize lipid-derived aldehydes generated in the plasma membrane Homo sapiens