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Literature summary extracted from

  • Wengert, M.; Ribeiro, M.C.; Abreu, T.P.; Coutinho-Silva, R.; Leao-Ferreira, L.R.; Pinheiro, A.A.; Caruso-Neves, C.
    Protein kinase C-mediated ATP stimulation of Na(+)-ATPase activity in LLC-PK1 cells involves a P2Y2 and/or P2Y4 receptor (2013), Arch. Biochem. Biophys., 535, 136-142.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.13 adenosine
-
 Sus scrofa
2.7.11.13 ATP
-
 Sus scrofa
2.7.11.13 phorbol myristate acetate
-
 Sus scrofa
7.2.2.1 ATP ATP-induced stimulation of proximal tubule Na+-ATPase activity is mediated by a protein kinase C-dependent receptor P2Y2 and/or P2Y4 pathway Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.13 calphostin C
-
 Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.1 ATP + H2O + Na/+in Sus scrofa
-
 ADP + phosphate + Na/+out
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.13 Sus scrofa
-
-
-
7.2.2.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.13 LLC-PK1 cell
-
 Sus scrofa
-
7.2.2.1 LLC-PK1 cell
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.13 ATP + histone
-
 Sus scrofa ADP + phosphorylated histone
-
 ?
7.2.2.1 ATP + H2O + Na/+in
-
 Sus scrofa ADP + phosphate + Na/+out
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.13 protein kinase C
-
 Sus scrofa
7.2.2.1 Na+-translocating ATPase
-
 Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.11.13 7
-
 assay at Sus scrofa

General Information

EC Number General Information Comment Organism
2.7.11.13 physiological function metabotropic P2Y receptor-mediates ATP stimulated Na+-ATPase activity through the activation of protein kinase C Sus scrofa