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Literature summary extracted from

  • Buchholz, J.; Schwentner, A.; Brunnenkan, B.; Gabris, C.; Grimm, S.; Gerstmeir, R.; Takors, R.; Eikmanns, B.J.; Blombach, B.
    Platform Engineering: Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate (2013), Appl. Environ. Microbiol., 79, 5566-5575.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.5.1 pyruvate + ubiquinone + H2O Corynebacterium glutamicum
-
 acetate + CO2 + ubiquinol
-
 ?
1.2.5.1 pyruvate + ubiquinone + H2O Corynebacterium glutamicum aceE A16
-
 acetate + CO2 + ubiquinol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.5.1 Corynebacterium glutamicum
-
-
-
1.2.5.1 Corynebacterium glutamicum aceE A16
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.5.1 pyruvate + ubiquinone + H2O
-
 Corynebacterium glutamicum acetate + CO2 + ubiquinol
-
 ?
1.2.5.1 pyruvate + ubiquinone + H2O
-
 Corynebacterium glutamicum aceE A16 acetate + CO2 + ubiquinol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.5.1 pqo
-
 Corynebacterium glutamicum
1.2.5.1 pyruvate:quinone oxidoreductase
-
 Corynebacterium glutamicum

General Information

EC Number General Information Comment Organism
1.2.5.1 malfunction inactivation of the pyruvate:quinone oxidoreductase results in a more efficient L-valine production in Corynebacterium glutamicum strain aceE A16 Corynebacterium glutamicum