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Literature summary extracted from

  • Lu, L.Y.; Hsu, Y.C.; Yang, Y.S.
    Spectrofluorometric assay for monoamine-preferring phenol sulfotransferase (SULT1A3) (2010), Anal. Biochem., 404, 241-243.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.1 dopamine substrate inhibition at concentrations higher than 0.03 mM Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.1 0.0068
-
 dopamine at pH 7.0 and 37°C Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + dopamine Homo sapiens
-
 adenosine 3',5'-bisphosphate + dopamine sulfate
-
 r
2.8.2.1 adenosine 3',5'-bisphosphate + dopamine sulfate Homo sapiens
-
 3'-phosphoadenylyl sulfate + dopamine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + 4-methylumbelliferone
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-methylumbelliferyl sulfate
-
 r
2.8.2.1 3'-phosphoadenylyl sulfate + dopamine
-
 Homo sapiens adenosine 3',5'-bisphosphate + dopamine sulfate
-
 r
2.8.2.1 adenosine 3',5'-bisphosphate + 4-methylumbelliferyl sulfate
-
 Homo sapiens 3'-phosphoadenylyl sulfate + 4-methylumbelliferone
-
 r
2.8.2.1 adenosine 3',5'-bisphosphate + dopamine sulfate
-
 Homo sapiens 3'-phosphoadenylyl sulfate + dopamine
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.8.2.1 M-PST
-
 Homo sapiens
2.8.2.1 monoamine-form phenol sulfotransferase
-
 Homo sapiens
2.8.2.1 SULT1A3
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.1 37
-
-
 Homo sapiens

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.8.2.1 30 45 about 60% activity at 30°C and about 90% activity at 45°C, no activity at 50°C Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.1 7
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.8.2.1 6.5 8.5 about 65% activity at pH 6.5 and about 50% activity at pH 8.5 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.8.2.1 0.174
-
 dopamine at pH 7.0 and 37°C Homo sapiens