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Literature summary extracted from

  • Herde, M.; Gärtner, K.; Köllner, T.G.; Fode, B.; Boland, W.; Gershenzon, J.; Gatz, C.; Tholl, D.
    Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT (2008), Plant Cell, 20, 1152-1168.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.144 expressed in Escherichia coli Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.3.144 additional information the enzyme is not localized to the plastids Arabidopsis thaliana
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Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.3.144 Mg2+ highest activity with 10 mM Mg2+ Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.144 geranylgeranyl diphosphate + H2O Arabidopsis thaliana the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores (E,E)-geranyllinalool + diphosphate
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?
4.2.3.144 geranylgeranyl diphosphate + H2O Arabidopsis thaliana Columbia ecotype the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores (E,E)-geranyllinalool + diphosphate
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?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.144 Arabidopsis thaliana Q93YV0
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4.2.3.144 Arabidopsis thaliana Columbia ecotype Q93YV0
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.144 leaf
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Arabidopsis thaliana
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.144 geranylgeranyl diphosphate + H2O the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores Arabidopsis thaliana (E,E)-geranyllinalool + diphosphate
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?
4.2.3.144 geranylgeranyl diphosphate + H2O no activity with geranyl diphosphate or farnesyl diphosphate Arabidopsis thaliana (E,E)-geranyllinalool + diphosphate
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?
4.2.3.144 geranylgeranyl diphosphate + H2O the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores Arabidopsis thaliana Columbia ecotype (E,E)-geranyllinalool + diphosphate
-
?
4.2.3.144 geranylgeranyl diphosphate + H2O no activity with geranyl diphosphate or farnesyl diphosphate Arabidopsis thaliana Columbia ecotype (E,E)-geranyllinalool + diphosphate
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?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.144 At1g61120
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Arabidopsis thaliana
4.2.3.144 GES
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Arabidopsis thaliana
4.2.3.144 TPS04/GES
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Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
4.2.3.144 Arabidopsis thaliana transcription is upregulated under conditions that induce (E,E)-geranyllinalool and 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthesis, including infestation of plants with larvae of the moth Plutella xylostella and treatment with the fungal peptide alamethicin or the octadecanoid mimic coronalon. Induction requires jasmonic acid but is independent from salicylic acid or ethylene up

General Information

EC Number General Information Comment Organism
4.2.3.144 malfunction transgenic Arabidopsis lines carrying T-DNA insertions in the TPS04 locus are deficient in (E,E)-geranyllinalool and 4,8,12-trimethyl-1,3,7,11-tridecatetraene synthesis Arabidopsis thaliana