Literature summary extracted from

Appleyard, M.V.C.L.; Sloan, J.; Kanan, G.; Heck, I.; Kinghorn, J.; Unkles, S.
The Aspergillus nidulans cnxF gene and its involvement in molybdopterin biosynthesis: molecular characterization and analysis of in vivo generated mutants (1998), J. Biol. Chem., 273, 14869-14876.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.8.1.11	gene cnxF, DNA and amino acid sequence determination and analysis, sequence comparison, genetic structure and organization	Aspergillus nidulans

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.8.1.11	G160D	radom mutagenesis, temperature-sensitive phenotype	Aspergillus nidulans
2.8.1.11	G178D	radom mutagenesis, temperature-sensitive phenotype	Aspergillus nidulans
2.8.1.11	G342S	radom mutagenesis., temperature-sensitive phenotype	Aspergillus nidulans
2.8.1.11	additional information	generation of several hundred cnx mutants by radom mutagenesis, activity analysis and phenotypes, overview	Aspergillus nidulans

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.1.11	Aspergillus nidulans	-	gene cnxF	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.8.1.11	CnxF protein	-	Aspergillus nidulans
2.8.1.11	molybdopterin synthase sulfurylase	-	Aspergillus nidulans

General Information

EC Number	General Information	Comment	Organism
2.8.1.11	additional information	the enzyme contains two potential nucleotide binding Gly-rich motifs (Gly-X-Gly-X-X-Gly) starting at residue positions 173 and 189	Aspergillus nidulans
2.8.1.11	physiological function	te enzyme is required for the conversion of precursor Z to molybdopterin	Aspergillus nidulans

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Release 2023.1 (January 2023)