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Literature summary extracted from

  • Bridger, S.L.; Clarkson, S.M.; Stirrett, K.; DeBarry, M.B.; Lipscomb, G.L.; Schut, G.J.; Westpheling, J.; Scott, R.A.; Adams, M.W.
    Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus (2011), J. Bacteriol., 193, 6498-6504.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.18 Pyrococcus furiosus Q8U1M0
-
-
1.8.1.19 Pyrococcus furiosus Q8U194 Q8U194: subunit beta (sudB, SuDH I)
-

Synonyms

EC Number Synonyms Comment Organism
1.8.1.18 coenzyme A-dependent NADPH sulfur oxidoreductase
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Pyrococcus furiosus
1.8.1.18 NSR
-
Pyrococcus furiosus
1.8.1.18 PF1186
-
Pyrococcus furiosus
1.8.1.19 PF1328
-
Pyrococcus furiosus
1.8.1.19 SuDH I
-
Pyrococcus furiosus

Expression

EC Number Organism Comment Expression
1.8.1.19 Pyrococcus furiosus following sulfur (S0) addition in deletion mutant NSR1 (deletion in NADPH:sulfur oxidoreductase, NSR) the expression of the gene encoding sulfide dehydrogenase SuDH I (sudB) is decreased to a lesser extent (5fold less) compared to the parent strain down
1.8.1.19 Pyrococcus furiosus following sulfur (S0) addition in deletion mutant MBX1 (deletion in membrane-bound oxidoreductase complex, MBX) the expression of the gene encoding sulfide dehydrogenase SuDH I (sudB) is increased 2fold, campared to 10fold increase in the parent strain up

General Information

EC Number General Information Comment Organism
1.8.1.18 malfunction the growth of the NADPH sulfur oxidoreductase deletion strain (NSR1) is unaffected, indicating that NSR is not essential for energy conservation during S(0) reduction. Two sulfide dehydrogenase isoenzymes provide a compensatory NADPH-dependent S(0) reduction system Pyrococcus furiosus
1.8.1.19 physiological function NADPH-dependent S0 reduction by SuDH I and SuDH II may be a mechanism to compensate for the reduction of S0 in the absence of NADPH:sulfur oxidoreductase (NSR) Pyrococcus furiosus