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Literature summary extracted from

  • Wienstroer, J.; Engqvist, M.K.; Kunz, H.H.; Fluegge, U.I.; Maurino, V.G.
    D-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants (2012), FEBS Lett., 586, 36-40.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.1.28 molecular biology D-lactate dehydrogenase is useful as a marker gene allowing positive selection of transgenic plants Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.28 additional information at media D-lactate concentrations greater than 5-10 mM the development of wild-type plants is arrested shortly after germination whereas plants overexpressing the endogenous D-lactate dehydrogenase detoxify D-lactate to pyruvate and survive, phenotypes, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.28 (R)-lactate + NAD+ Arabidopsis thaliana
-
 pyruvate + NADH + H+
-
 r
1.1.1.28 (R)-lactate + NAD+ Arabidopsis thaliana Columbia-0
-
 pyruvate + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.28 Arabidopsis thaliana
-
-
-
1.1.1.28 Arabidopsis thaliana Columbia-0
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.28 leaf
-
 Arabidopsis thaliana
-
1.1.1.28 seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.28 (R)-lactate + NAD+
-
 Arabidopsis thaliana pyruvate + NADH + H+
-
 r
1.1.1.28 (R)-lactate + NAD+
-
 Arabidopsis thaliana Columbia-0 pyruvate + NADH + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.28 D-LDH
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.28 NAD+
-
 Arabidopsis thaliana
1.1.1.28 NADH
-
 Arabidopsis thaliana