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Literature summary extracted from

  • Kingsbury, J.M.; McCusker, J.H.
    Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation (2010), Eukaryot. Cell, 9, 729-737.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.39 Candida albicans
-
-
-
2.7.1.39 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.39 ATP + L-homoserine
-
 Saccharomyces cerevisiae ADP + O-phospho-L-homoserine
-
 ?
2.7.1.39 ATP + L-homoserine
-
 Candida albicans ADP + O-phospho-L-homoserine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.39 Thr1p
-
 Saccharomyces cerevisiae
2.7.1.39 Thr1p
-
 Candida albicans

General Information

EC Number General Information Comment Organism
2.7.1.39 malfunction homoserine kinase deletion mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation Candida albicans
2.7.1.39 malfunction homoserine kinase deletion mutants are extremely serum sensitive and hypersensitive to DNA-damaging agents Saccharomyces cerevisiae