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Literature summary extracted from

  • Stark, A.; Zeiger, E.; Pagano, D.
    Glutathione mutagenesis in Salmonella typhimurium is a gamma-glutamyltranspeptidase-enhanced process involving active oxygen species (1988), Carcinogenesis, 9, 771-777.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.19.13 Salmonella enterica subsp. enterica serovar Typhimurium
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General Information

EC Number General Information Comment Organism
3.4.19.13 physiological function mutagenic effect of glutathione follows a model of an indirect mechanism, i.e. cleavage of glutathione by gamma-glutamyltranspeptidase, followed by facile autooxidation of the resulting cysteinylglycine, with the production of free radicals which lead to the (pen)ultimate mutagen, H2O2 Salmonella enterica subsp. enterica serovar Typhimurium