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Literature summary extracted from

  • Chu, H.N.; Kobayashi, J.; Mikami, B.; Yagi, T.
    The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti (2011), Biosci. Biotechnol. Biochem., 75, 388-390.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.107 overexpression in Escherichia coli strain BL21(DE3) Mesorhizobium loti

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.107 pyridoxal + NAD+ Mesorhizobium loti
-
 4-pyridoxolactone + NADH + H+
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.107 Mesorhizobium loti
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.107 pyridoxal + NAD+
-
 Mesorhizobium loti 4-pyridoxolactone + NADH + H+
-
 ir
1.1.1.107 pyridoxal + NAD+ via pyridoxal hemiacetal Mesorhizobium loti 4-pyridoxolactone + NADH + H+
-
 ir

Synonyms

EC Number Synonyms Comment Organism
1.1.1.107 PLDH
-
 Mesorhizobium loti

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.107 NAD+
-
 Mesorhizobium loti

General Information

EC Number General Information Comment Organism
1.1.1.107 evolution the enzyme belongs to the short-chain dehydrogenase/reductase enzyme family Mesorhizobium loti
1.1.1.107 additional information structure analysis, homology modeling using the crystal structure of (S)-1-phenylethanol dehydrogenase, PDB ID 2EW8, molecular replacement, overview Mesorhizobium loti
1.1.1.107 physiological function the enzyme is involved in the degradation pathway I of pyridoxine, a vitamin B6 compound Mesorhizobium loti