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Literature summary extracted from

  • Solis-Oviedo, R.L.; Martinez-Morales, F.; Geiger, O.; Sohlenkamp, C.
    Functional and topological analysis of phosphatidylcholine synthase from Sinorhizobium meliloti (2012), Biochim. Biophys. Acta, 1821, 573-581.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.24 expressed in Escherichia coli BL21(DE3).pLysS cells Sinorhizobium meliloti

Protein Variants

EC Number Protein Variants Comment Organism
2.7.8.24 D56A inactive Sinorhizobium meliloti
2.7.8.24 D56E inactive Sinorhizobium meliloti
2.7.8.24 D56N inactive Sinorhizobium meliloti
2.7.8.24 D59A inactive Sinorhizobium meliloti
2.7.8.24 D59E inactive Sinorhizobium meliloti
2.7.8.24 D59N inactive Sinorhizobium meliloti
2.7.8.24 D81A inactive Sinorhizobium meliloti
2.7.8.24 D81E the mutant shows 14% of wild type activity Sinorhizobium meliloti
2.7.8.24 D81N the mutant shows 21% of wild type activity Sinorhizobium meliloti
2.7.8.24 D85A inactive Sinorhizobium meliloti
2.7.8.24 D85E inactive Sinorhizobium meliloti
2.7.8.24 D85N inactive Sinorhizobium meliloti
2.7.8.24 G229D inactive Sinorhizobium meliloti
2.7.8.24 G60A inactive Sinorhizobium meliloti
2.7.8.24 G77A inactive Sinorhizobium meliloti
2.7.8.24 G77D inactive Sinorhizobium meliloti
2.7.8.24 H20A inactive Sinorhizobium meliloti
2.7.8.24 H20L the mutant shows 62% of wild type activity Sinorhizobium meliloti
2.7.8.24 L72A the mutant shows 46% of wild type activity Sinorhizobium meliloti
2.7.8.24 L72R inactive Sinorhizobium meliloti
2.7.8.24 L80A the mutant shows 85% of wild type activity Sinorhizobium meliloti
2.7.8.24 R64A the mutant shows 67% of wild type activity Sinorhizobium meliloti
2.7.8.24 T23A inactive Sinorhizobium meliloti
2.7.8.24 T23S the mutant shows 67% of wild type activity Sinorhizobium meliloti
2.7.8.24 V83A the mutant shows 39% of wild type activity Sinorhizobium meliloti
2.7.8.24 W142A inactive Sinorhizobium meliloti
2.7.8.24 Y123A the mutant shows less than 20% of wild type activity Sinorhizobium meliloti
2.7.8.24 Y86A inactive Sinorhizobium meliloti
2.7.8.24 Y89A inactive Sinorhizobium meliloti

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.24 membrane a transmembrane protein Sinorhizobium meliloti 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.24 Sinorhizobium meliloti Q9KJY8
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.24 CDP-diacylglycerol + choline
-
 Sinorhizobium meliloti CMP + phosphatidylcholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.24 PCS
-
 Sinorhizobium meliloti