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Literature summary extracted from

  • Freel Meyers, C.L.; Oberthür, M.; Heide, L.; Kahne, D.; Walsh, C.T.
    Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN (2004), Biochemistry, 43, 15022-15036.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.12 Streptomyces niveus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.12 2 carbamoyl phosphate + N,N'-bis(7-[[(2R,3R,4S,5R)-3,4-dihydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-3-methyl-1H-pyrrole-2,4-dicarboxamide the tandem action of CouL, CouM, CouP, and NovN generates a biscarbamoyl analogue of the pseudodimer coumermycin A1 Streptomyces niveus 2 phosphate + (3-methyl-1H-pyrrole-2,4-diyl)bis[carbonylimino(4-hydroxy-8-methyl-2-oxo-2H-chromene-3,7-diyl)oxy-(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2,4-diyl] dicarbamate
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Synonyms

EC Number Synonyms Comment Organism
2.1.3.12 NovN
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Streptomyces niveus