EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.1.1.68 | x-ray crystallographic structures of Lp OMT1 are reported in open conformational state, apo- and holoenzyme forms and, most significantly, in a closed conformational state complexed with the products S-adenosyl-L-homocysteine and sinapaldehyde. The product-bound complex reveals the postmethyl-transfer organization of COMTs catalytic groups with reactant molecules and the fully formed phenolic-ligand binding site. The core scaffold of the phenolic ligand forges a hydrogen-bonding network involving the 4-hydroxy group that anchors the aromatic ring and thereby permits only metahydroxyl groups to be positioned for transmethylation | Lolium perenne |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.68 | Lolium perenne | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.68 | S-adenosyl-L-methionine + 5-hydroxyconiferaldehyde | - |
Lolium perenne | ? | - |
? | |
2.1.1.68 | S-adenosyl-L-methionine + 5-hydroxyferulic acid | - |
Lolium perenne | S-adenosyl-L-homocysteine + sinapic acid | - |
? | |
2.1.1.68 | S-adenosyl-L-methionine + caffeic acid | - |
Lolium perenne | ? | - |
? | |
2.1.1.68 | S-adenosyl-L-methionine + caffeoyl alcohol | - |
Lolium perenne | ? | - |
? | |
2.1.1.68 | S-adenosyl-L-methionine + caffeoyl aldehyde | - |
Lolium perenne | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.68 | Lp OMT1 | - |
Lolium perenne |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.1.1.68 | 22 | - |
assay at | Lolium perenne |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.1.1.68 | 7.5 | - |
assay at | Lolium perenne |