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Literature summary extracted from

  • Ikeda, T.; Ohsugi, T.; Kimura, T.; Matsushita, S.; Maeda, Y.; Harada, S.; Koito, A.
    The antiretroviral potency of APOBEC1 deaminase from small animal species (2008), Nucleic Acids Res., 36, 6859-6871.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.36
-
 Mus musculus
3.5.4.36
-
 Rattus norvegicus
3.5.4.36
-
 Mustela putorius furo
3.5.4.36
-
 Oryctolagus cuniculus
3.5.4.36
-
 Mesocricetus auratus

Protein Variants

EC Number Protein Variants Comment Organism
3.5.4.36 E63A inactive mutant enzyme. The ability of the mutant proteins to restrict the infectivity of wild-type and DELTAvif viruses are severely, but not completely impaired Oryctolagus cuniculus
3.5.4.36 E63Q inactive mutant enzyme. The ability of the mutant proteins to restrict the infectivity of wild-type and DELTAvif viruses are severely, but not completely impaired Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.36 Mesocricetus auratus Q9EQP0
-
-
3.5.4.36 Mus musculus P51908
-
-
3.5.4.36 Mustela putorius furo B2NIW5
-
-
3.5.4.36 Oryctolagus cuniculus P47855
-
-
3.5.4.36 Rattus norvegicus P38483
-
-
3.5.4.37 Homo sapiens P41238
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.36 additional information APOBEC1 possesses antiviral activity. It is capable of inhibiting the infectivity of various lentiviruses in tissue culture models Mus musculus ?
-
 ?
3.5.4.36 additional information APOBEC1 possesses antiviral activity. It is capable of inhibiting the infectivity of various lentiviruses in tissue culture models Rattus norvegicus ?
-
 ?
3.5.4.36 additional information APOBEC1 possesses antiviral activity. It is capable of inhibiting the infectivity of various lentiviruses in tissue culture models Mustela putorius furo ?
-
 ?
3.5.4.36 additional information APOBEC1 possesses antiviral activity. It is capable of inhibiting the infectivity of various lentiviruses in tissue culture models Oryctolagus cuniculus ?
-
 ?
3.5.4.36 additional information APOBEC1 possesses antiviral activity. It is capable of inhibiting the infectivity of various lentiviruses in tissue culture models Mesocricetus auratus ?
-
 ?
3.5.4.37 additional information human APOBEC1 possesses no antiviral activity Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.4.36 APOBEC1 catalytic component of an RNA-editing complex Mus musculus
3.5.4.36 APOBEC1 catalytic component of an RNA-editing complex Rattus norvegicus
3.5.4.36 APOBEC1 catalytic component of an RNA-editing complex Mustela putorius furo
3.5.4.36 APOBEC1 catalytic component of an RNA-editing complex Oryctolagus cuniculus
3.5.4.36 APOBEC1 catalytic component of an RNA-editing complex Mesocricetus auratus
3.5.4.37 APOBEC1 catalytic component of an RNA-editing complex Homo sapiens

General Information

EC Number General Information Comment Organism
3.5.4.36 physiological function unlike their human counterparts, APOBEC1 in a wide range of mammalian species may function as a defense mechanism regulating retroelements Mus musculus
3.5.4.36 physiological function unlike their human counterparts, APOBEC1 in a wide range of mammalian species may function as a defense mechanism regulating retroelements Rattus norvegicus
3.5.4.36 physiological function unlike their human counterparts, APOBEC1 in a wide range of mammalian species may function as a defense mechanism regulating retroelements Mustela putorius furo
3.5.4.36 physiological function unlike their human counterparts, APOBEC1 in a wide range of mammalian species may function as a defense mechanism regulating retroelements Oryctolagus cuniculus
3.5.4.36 physiological function unlike their human counterparts, APOBEC1 in a wide range of mammalian species may function as a defense mechanism regulating retroelements Mesocricetus auratus