EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.20 | expression in Mycobacterium smegmatis | Mycobacterium tuberculosis |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.3.1.20 | S126A | no detectable activity | Mycobacterium tuberculosis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.20 | 0.39 | - |
palmitoyl-CoA | pH 7.0, 37°C | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.20 | Mycobacterium tuberculosis | P9WQP3 | - |
- |
2.3.1.20 | Mycobacterium tuberculosis H37Rv | P9WQP3 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.20 | 1,2-dipalmitoyl-rac-glycerol + palmitoyl-CoA | - |
Mycobacterium tuberculosis | rac-tripalmitoylglycerol + CoA | - |
? | |
2.3.1.20 | 1,2-dipalmitoyl-rac-glycerol + palmitoyl-CoA | - |
Mycobacterium tuberculosis H37Rv | rac-tripalmitoylglycerol + CoA | - |
? | |
2.3.1.20 | additional information | enzyme mediates the transesterification of diacylglycerol using long-chain acyl-CoA as acyl donors. In addition, it functions as mycolyltransferase, a docking model suggests that palmitoleoyl-coenzyme A and 1,2-dipalmitin occupy the same active site as trehalose 6,6-dimycolate and trehalose 6-monomycolate | Mycobacterium tuberculosis | ? | - |
? | |
2.3.1.20 | additional information | enzyme mediates the transesterification of diacylglycerol using long-chain acyl-CoA as acyl donors. In addition, it functions as mycolyltransferase, a docking model suggests that palmitoleoyl-coenzyme A and 1,2-dipalmitin occupy the same active site as trehalose 6,6-dimycolate and trehalose 6-monomycolate | Mycobacterium tuberculosis H37Rv | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.20 | FBPA | - |
Mycobacterium tuberculosis |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.20 | 0.92 | - |
palmitoyl-CoA | pH 7.0, 37°C | Mycobacterium tuberculosis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.3.1.20 | physiological function | upon overexpression in Mycobacterium smegmatis mc2155, cell morphology is changed and the cells become grossly enlarged. A massive formation of lipid bodies and a change in lipid pattern is observed simultaneously | Mycobacterium tuberculosis |