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Literature summary extracted from

  • Wu, K.; Lai, X.; Guo, X.; Hu, J.; Xiang, X.; Huang, L.
    Interplay between primase and replication factor C in the hyperthermophilic archaeon Sulfolobus solfataricus (2006), Mol. Microbiol., 63, 826-837.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.B16 NTP + n NTP Saccharolobus solfataricus the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea N(pN)n + n diphosphate
-
 ?
2.7.7.B16 NTP + n NTP Saccharolobus solfataricus P2 the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea N(pN)n + n diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.B16 Saccharolobus solfataricus Q9UWW1 and Q97Z83 Q9UWW1: large subunit, Q97Z83: small subunit
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2.7.7.B16 Saccharolobus solfataricus P2 Q9UWW1 and Q97Z83 Q9UWW1: large subunit, Q97Z83: small subunit
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.B16 NTP + n NTP the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea Saccharolobus solfataricus N(pN)n + n diphosphate
-
 ?
2.7.7.B16 NTP + n NTP the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea Saccharolobus solfataricus P2 N(pN)n + n diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.B16 heterodimer
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 Saccharolobus solfataricus