EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.39 | expressed in Escherichia coli | Eimeria tenella |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.39 | corytuberine | - |
Eimeria tenella |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.39 | 0.0228 | - |
malonyl-CoA | pH 6.8, 28°C | Eimeria tenella |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.39 | apicoplast | - |
Eimeria tenella | 20011 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.39 | 38800 | - |
calculated from cDNA | Eimeria tenella |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.39 | Eimeria tenella | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.3.1.39 | proteolytic modification | computer analysis predicts that EtMCAT protein contains a 20 aa N-terminal signal peptide plus 37 aa transit peptide for targeting and translocating into the apicoplast | Eimeria tenella |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.39 | malonyl-CoA + acyl-carrier protein | alpha-ketoglutarate dehydrogenase (KDH)-coupled assay system is used: KDH-dependent consumption of coenzyme A (CoA) generated by MCAT is accompanied by a reduction of nicotinamide adenine dinucleotide (NAD+) to NADH | Eimeria tenella | CoA + malonyl-[acyl-carrier protein] | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.39 | EtMCAT | - |
Eimeria tenella |
2.3.1.39 | FabD | - |
Eimeria tenella |
2.3.1.39 | malonyl-CoA:acyl carrier protein transacylase | - |
Eimeria tenella |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.1.39 | 28 | - |
assay at | Eimeria tenella |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.1.39 | 6.8 | - |
assay at | Eimeria tenella |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.39 | 0.01647 | - |
pH 6.8, 28°C | Eimeria tenella | corytuberine |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.3.1.39 | malfunction | functional replacement of the fabD gene with amber mutation of Escherichia coli temperature-sensitive LA2-89 strain by Eimeria tenella EtMCAT demonstrates that EcFabD and EtMCAT perform the same biochemical function | Eimeria tenella |