Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Prasad, S.S.; Garg, A.; Agarwal, A.K.
    Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria (2011), J. Lipid Res., 52, 451-462.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.51 expression in HEK-293 cell Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.51 0.0048
-
 1-oleoyl-sn-glycerol 3-phosphate pH 7.4, 30°C Homo sapiens
2.3.1.51 0.0055
-
 1-oleoyl-sn-glycerol 3-phosphate pH 7.4, 37°C Homo sapiens
2.3.1.51 0.0163
-
 oleoyl-CoA pH 7.4, 37°C Homo sapiens
2.3.1.51 0.0215
-
 oleoyl-CoA pH 7.4, 30°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.51 endoplasmic reticulum
-
 Homo sapiens 5783
-
2.3.1.51 mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.51 43380
-
 x * 43380, claculated Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.51 Homo sapiens Q9NRZ7
-
-
2.3.1.51 Homo sapiens Q9NUQ2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.51 adipose tissue
-
 Homo sapiens
-
2.3.1.51 kidney high expression Homo sapiens
-
2.3.1.51 liver
-
 Homo sapiens
-
2.3.1.51 lung
-
 Homo sapiens
-
2.3.1.51 additional information isoform AGPAT3 appears to be ubiquitously expressed across the tissues examined. Comparison of isoforms AGPAT3, AGPAT4, AGPAT5 expression in different tissues Homo sapiens
-
2.3.1.51 pancreas high expression Homo sapiens
-
2.3.1.51 spleen
-
 Homo sapiens
-
2.3.1.51 testis high expression Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.51 arachidonoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate about half of the rate with oleoyl-CoA Homo sapiens CoA + 1-oleoyl-2-arachidonoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 heptadecanoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate about half of the rate with oleoyl-CoA Homo sapiens CoA + 1-oleoyl-2-heptadecanoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 linoleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate about half of the rate with oleoyl-CoA Homo sapiens CoA + 1-oleoyl-2-linoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 additional information isoform AGPAT3 shows broad preference for lysophosphatidic acids containing saturated or unsaturated fatty acids C16:0-C20:4 and significant esterification of lysophosphatidylinositol in the presence of oleoyl-CoA Homo sapiens ?
-
 ?
2.3.1.51 additional information isoform AGPAT5 demonstrates significant acyltransferase activity toward lysophosphatidylethanolamine in the presence of oleoyl-CoA Homo sapiens ?
-
 ?
2.3.1.51 oleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate both substrates are preferred Homo sapiens CoA + 1,2-dioleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 palmitoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate about 40% of the rate with oleoyl-CoA Homo sapiens CoA + 1-oleoyl-2-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 stearoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate about 40% of the rate with oleoyl-CoA Homo sapiens CoA + 1-oleoyl-2-stearoyl-sn-glycerol 3-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.51 ? x * 43380, claculated Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.3.1.51 AGPAT3
-
 Homo sapiens
2.3.1.51 AGPAT5
-
 Homo sapiens