EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.1.51 | medicine | expression of isoform AGPAT11 mRNA is signifi cantly upregulated in human breast, cervical, and colorectal cancer tissues | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.51 | expression in CHO cell, HeLa cell and HEK-293 cell | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.51 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.51 | Homo sapiens | Q7L5N7 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
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EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.51 | heptadecanoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
Homo sapiens | CoA + 1-oleoyl-2-heptadecanoyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.51 | linoleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
Homo sapiens | CoA + 1-oleoyl-2-linoleoyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.51 | additional information | isoform AGPAT11 shows broad preferences for the lysophosphatidic acid containing saturated fatty acids C16:0-C18:0, including lysophosphatidic acid containing oleic acid. Lysophosphatidic acid with fatty acid C20:4 is acylated at only about one-half maximal rate compared with others. The preferred acyl donor follows the decreasing order of C18:1,C16:0, C18:2, C17:0. Fatty acyl-CoA consisting of short-chain fatty acids C8:0 to C13:0 and very long-chain from C20:0 to C26:0 are not substrates. Enzyme does not display glycerol-3-phosphate acyltransferase activity | Homo sapiens | ? | - |
? | |
2.3.1.51 | oleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate | both substrates are preferred | Homo sapiens | CoA + 1,2-dioleoyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.51 | palmitoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
Homo sapiens | CoA + 1-oleoyl-2-palmitoyl-sn-glycerol 3-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.51 | AGPAT11 | - |
Homo sapiens |
2.3.1.51 | LPCAT2 | - |
Homo sapiens |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.3.1.51 | Homo sapiens | expression of isoform AGPAT11 mRNA is significantly upregulated in human breast, cervical, and colorectal cancer tissues | up |