Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mikusova, K.; Belanova, M.; Kordulakova, J.; Honda, K.; McNeil, M.; Mahapatra, S.; Crick, D.; Brennan, P.
    Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall (2006), J. Bacteriol., 188, 6592-6598.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.287 expressed in Mycobacterium smegmatis mc2155 cells Mycobacterium tuberculosis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.287 cell wall
-
 Mycobacterium tuberculosis 5618
-
2.4.1.287 membrane
-
 Mycobacterium tuberculosis 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.287 33863
-
 x * 33863, calculated from amino acid sequence Mycobacterium tuberculosis
2.4.1.288 71506
-
 x * 71506, calculated from amino acid sequence Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.287 Mycobacterium tuberculosis
-
-
-
2.4.1.287 Mycobacterium tuberculosis H37Rv
-
-
-
2.4.1.288 Mycobacterium tuberculosis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.287 Talon resin column chromatography Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.287 additional information the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf Mycobacterium tuberculosis ?
-
 ?
2.4.1.287 additional information the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf Mycobacterium tuberculosis H37Rv ?
-
 ?
2.4.1.287 UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?
2.4.1.287 UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis H37Rv UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?
2.4.1.288 UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?
2.4.1.288 UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis H37Rv UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.287 ? x * 33863, calculated from amino acid sequence Mycobacterium tuberculosis
2.4.1.288 ? x * 71506, calculated from amino acid sequence Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
2.4.1.287 galactosyl transferase
-
 Mycobacterium tuberculosis
2.4.1.287 GalTr
-
 Mycobacterium tuberculosis
2.4.1.287 Rv3782
-
 Mycobacterium tuberculosis
2.4.1.288 galactosyl transferase
-
 Mycobacterium tuberculosis
2.4.1.288 GalTr
-
 Mycobacterium tuberculosis
2.4.1.288 GlfT
-
 Mycobacterium tuberculosis
2.4.1.288 Rv3808c
-
 Mycobacterium tuberculosis

General Information

EC Number General Information Comment Organism
2.4.1.287 physiological function the enzyme is involved in biosynthesis of the mycobacterial cell wall Mycobacterium tuberculosis
2.4.1.288 metabolism the enzyme catalyzes the formation of both beta-5-linked and beta-6-linked galactofuranoses and is responsible for the synthesis of the bulk galactan portion of AG Mycobacterium tuberculosis