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Literature summary extracted from

  • Mishanina, T.V.; Koehn, E.M.; Conrad, J.A.; Palfey, B.A.; Lesley, S.A.; Kohen, A.
    Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase (2012), J. Am. Chem. Soc., 134, 4442-4448.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.148 Thermotoga maritima Q9WYT0
-
-
2.1.1.148 Thermotoga maritima ATCC 43589 Q9WYT0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.148
-
 Thermotoga maritima

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.148 5,10-methylenetetrahydrofolate + dUMP + FADH2
-
 Thermotoga maritima dTMP + tetrahydrofolate + FAD
-
 ?
2.1.1.148 5,10-methylenetetrahydrofolate + dUMP + FADH2
-
 Thermotoga maritima ATCC 43589 dTMP + tetrahydrofolate + FAD
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.148 FDTS
-
 Thermotoga maritima
2.1.1.148 flavin-dependent thymidylate synthase
-
 Thermotoga maritima

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.148 FAD
-
 Thermotoga maritima