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Literature summary extracted from

  • Wang, Z.; Kohen, A.
    Thymidylate synthase catalyzed H-transfers: two chapters in one tale (2010), J. Am. Chem. Soc., 132, 9820-9825.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.45
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.45 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.45
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.45 5,10-methylenetetrahydrofolate + dUMP
-
 Homo sapiens dihydrofolate + dTMP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.45 TSase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.45 N5,N10-methylenetetrahydrofolate
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.1.1.45 physiological function the enzyme is essential for the de novo synthesis of DNA Homo sapiens