EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.53 | Cbz-Leu-DL-Abu-CONH-(CH2)3-(4-methylpiperazin-1-yl) | - |
Sus scrofa | |
3.4.22.53 | Cbz-Leu-DL-Abu-CONH-(CH2)3-2-methoxyadenin-9-yl | - |
Sus scrofa | |
3.4.22.53 | Cbz-Leu-DL-Abu-CONH-(CH2)3-adenin-9-yl | - |
Sus scrofa | |
3.4.22.53 | Cbz-Leu-DL-Abu-CONH-(CH2)3-cytosin-3-yl | - |
Sus scrofa | |
3.4.22.53 | Cbz-Leu-DL-Abu-CONH-(CH2)3-morpholine | - |
Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)2-N-(CH3)2 | - |
Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)3-(4-methylpiperazin-1-yl) | - |
Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)3-2-methoxyadenin-9-yl | - |
Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)3-adenin-9-yl | best inhibitor | Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)3-cytosin-3-yl | - |
Sus scrofa | |
3.4.22.53 | CBZ-Leu-DL-Phe-CONH-(CH2)3-N-(CH3)2 | - |
Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.53 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.53 | kidney | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.53 | succinyl-Leu-Tyr-7-amido-4-methylcoumarin + H2O | - |
Sus scrofa | succinyl-Leu-Tyr + 7-amino-4-methylcoumarin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.53 | Cal II | - |
Sus scrofa |
3.4.22.53 | calpain II | - |
Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.22.53 | 0.000041 | - |
Cbz-Leu-DL-Abu-CONH-(CH2)3-morpholine | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000068 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)3-adenin-9-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.00007 | - |
Cbz-Leu-DL-Abu-CONH-(CH2)3-adenin-9-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000077 | - |
Cbz-Leu-DL-Abu-CONH-(CH2)3-2-methoxyadenin-9-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000209 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)3-2-methoxyadenin-9-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000286 | - |
Cbz-Leu-DL-Abu-CONH-(CH2)3-(4-methylpiperazin-1-yl) | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000438 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)3-cytosin-3-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.000844 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)3-N-(CH3)2 | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.00114 | - |
Cbz-Leu-DL-Abu-CONH-(CH2)3-cytosin-3-yl | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.00352 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)2-N-(CH3)2 | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa | |
3.4.22.53 | 0.00636 | - |
CBZ-Leu-DL-Phe-CONH-(CH2)3-(4-methylpiperazin-1-yl) | in 50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA, 0.1% CHAPS, pH 7.5, 10 mM dithiothreitol, 5 mM CaCl2, and less than 5% (v/v) DMSO, temperature not specified in the publication | Sus scrofa |