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Literature summary extracted from

  • Grochowski, L.L.; Xu, H.; White, R.H.
    Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate (2006), J. Bacteriol., 188, 3192-3198.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.26 expression in Escherichia coli BL21 Methanocaldococcus jannaschii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.26 0.256
-
 isopentenyl phosphate pH 7.5, 55°C Methanocaldococcus jannaschii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.26 ATP + isopentenyl phosphate Methanocaldococcus jannaschii involved in the mevalonate pathway ADP + isopentenyl diphosphate
-
 ?
2.7.4.26 ATP + isopentenyl phosphate Methanocaldococcus jannaschii DSM 2661 involved in the mevalonate pathway ADP + isopentenyl diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.26 Methanocaldococcus jannaschii Q60352
-
-
2.7.4.26 Methanocaldococcus jannaschii DSM 2661 Q60352
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.26 ATP + isopentenyl phosphate strictly specific for ATP Methanocaldococcus jannaschii ADP + isopentenyl diphosphate
-
 ?
2.7.4.26 ATP + isopentenyl phosphate involved in the mevalonate pathway Methanocaldococcus jannaschii ADP + isopentenyl diphosphate
-
 ?
2.7.4.26 ATP + isopentenyl phosphate strictly specific for ATP Methanocaldococcus jannaschii DSM 2661 ADP + isopentenyl diphosphate
-
 ?
2.7.4.26 ATP + isopentenyl phosphate involved in the mevalonate pathway Methanocaldococcus jannaschii DSM 2661 ADP + isopentenyl diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.4.26 MJ0044
-
 Methanocaldococcus jannaschii

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.4.26 330
-
 isopentenyl phosphate pH 7.5, 55°C Methanocaldococcus jannaschii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.4.26 9
-
-
 Methanocaldococcus jannaschii

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.4.26 7 9
-
 Methanocaldococcus jannaschii