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Literature summary extracted from

  • Funk, C.; Koepp, A.E.; Croteau, R.
    Catabolism of camphor in tissue cultures and leaf disks of common sage (Salvia officinalis) (1992), Arch. Biochem. Biophys., 294, 306-313.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.161 clotrimazole 84% inhibition at 0.05 mM Salvia officinalis
1.14.13.161 CO 73% inhibition at CO:O2 ratio of 9:1, activity is partially restored by blue light Salvia officinalis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.161 membrane light membrane fraction Salvia officinalis 16020
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.161 Salvia officinalis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.161 cell suspension culture
-
 Salvia officinalis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.161 (+)-camphor + NADPH + H+ + O2
-
 Salvia officinalis (+)-6-exo-hydroxycamphor + NADP+ + H2O
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.13.161 7
-
-
 Salvia officinalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.161 cytochrome P450 enzyme is a cytochrome P450-dependent monooxygenase Salvia officinalis
1.14.13.161 NADPH absolute requirement for NADPH and O2 Salvia officinalis

General Information

EC Number General Information Comment Organism
1.14.13.161 physiological function pathway for camphor degradation follows the oxidative ring opening sequence from (+)-camphor to 6-hydroxycamphor, 6-oxocamphor, alpha-campholonic acid, and 2-hydroxy-alpha-campholonic acid. The catabolism of camphor via 1,2-campholide is a minor degradative pathway Salvia officinalis