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Literature summary extracted from
- In vitro kinetic interactions of pyridostigmine, physostigmine and soman with erythrocyte and muscle acetylcholinesterase from different species (2011), Toxicol. Lett., 206, 41-46.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.7 | soman | pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman | Cavia porcellus |  |
| 3.1.1.7 | soman | pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman | Homo sapiens | |
| 3.1.1.7 | soman | pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman | Macaca mulatta | |
| 3.1.1.7 | soman | pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman | Sus scrofa | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | Cavia porcellus | - |
- |
- |
| 3.1.1.7 | Homo sapiens | - |
- |
- |
| 3.1.1.7 | Macaca mulatta | - |
- |
- |
| 3.1.1.7 | Sus scrofa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | erythrocyte | - |
Cavia porcellus | - |
| 3.1.1.7 | erythrocyte | - |
Homo sapiens | - |
| 3.1.1.7 | erythrocyte | - |
Sus scrofa | - |
| 3.1.1.7 | erythrocyte | - |
Macaca mulatta | - |
| 3.1.1.7 | intercostal muscle | - |
Cavia porcellus | - |
| 3.1.1.7 | intercostal muscle | - |
Homo sapiens | - |
| 3.1.1.7 | intercostal muscle | - |
Sus scrofa | - |
| 3.1.1.7 | intercostal muscle | - |
Macaca mulatta | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.7 | acetylcholine + H2O | - |
Cavia porcellus | choline + acetate | - |
? | |
| 3.1.1.7 | acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
| 3.1.1.7 | acetylcholine + H2O | - |
Sus scrofa | choline + acetate | - |
? | |
| 3.1.1.7 | acetylcholine + H2O | - |
Macaca mulatta | choline + acetate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.7 | AChE | - |
Cavia porcellus |
| 3.1.1.7 | AChE | - |
Homo sapiens |
| 3.1.1.7 | AChE | - |
Sus scrofa |
| 3.1.1.7 | AChE | - |
Macaca mulatta |
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Release 2023.1 (January 2023)
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