EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.22 | Thermus thermophilus | - |
- |
- |
6.3.5.6 | Thermus thermophilus | - |
- |
- |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.3.5.6 | homodimer | - |
Thermus thermophilus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.22 | AsnRS | - |
Thermus thermophilus |
6.1.1.22 | Asparaginyl-tRNA synthetase | - |
Thermus thermophilus |
6.3.5.6 | AsnRS | - |
Thermus thermophilus |
6.3.5.6 | Asparaginyl-tRNA synthetase | - |
Thermus thermophilus |
EC Number | Organism | Comment | Expression |
---|---|---|---|
6.1.1.22 | Thermus thermophilus | engineering of aspartyladenylate, AspAMP, specificity into asparaginyl-tRNA synthetase, AsnRS, whose substrate is asparaginyl-adenylate by CPD method, that uses a polar-hydrogen energy function for protein interactions and a coulomb/accessible surface area model for solvent effects, method development, overview. Application of an all-atom energy for protein interactions and a residue-pairwise generalized Born model for solvent effects, overview. The conformations and interactions are well maintained in molecular dynamics simulations and the sequences have an inverted specificity, favoring AspAMP over AsnAMP | additional information |