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Literature summary extracted from

  • Li, X.; Ilarslan, H.; Brachova, L.; Qian, H.R.; Li, L.; Che, P.; Wurtele, E.S.; Nikolau, B.J.
    Reverse-genetic analysis of the two biotin-containing subunit genes of the heteromeric acetyl-coenzyme A carboxylase in Arabidopsis indicates a unidirectional functional redundancy (2011), Plant Physiol., 155, 293-314.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.4.1.2 plastid
-
Arabidopsis thaliana 9536
-

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.2 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.2 embryo
-
Arabidopsis thaliana
-
6.4.1.2 endosperm
-
Arabidopsis thaliana
-
6.4.1.2 flower
-
Arabidopsis thaliana
-
6.4.1.2 seed
-
Arabidopsis thaliana
-
6.4.1.2 seedling
-
Arabidopsis thaliana
-
6.4.1.2 silique
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3-
-
Arabidopsis thaliana ADP + malonyl-CoA + phosphate
-
?

Subunits

EC Number Subunits Comment Organism
6.4.1.2 heteromer the enzyme is composed of four subunits: biotin carboxyl carrier protein, biotin carboxylase, alpha-carboxyltransferase, and beta-carboxyltransferase Arabidopsis thaliana

Synonyms

EC Number Synonyms Comment Organism
6.4.1.2 ACCase
-
Arabidopsis thaliana
6.4.1.2 BCCP1 subunit Arabidopsis thaliana
6.4.1.2 BCCP2 subunit Arabidopsis thaliana
6.4.1.2 CAC1A gene name for subunit BCCP1 Arabidopsis thaliana
6.4.1.2 CAC1B gene name for subunit BCCP2 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.2 ATP
-
Arabidopsis thaliana
6.4.1.2 biotin
-
Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
6.4.1.2 Arabidopsis thaliana accumulation of BCCP1 is 5ffold higher than that of BCCP2 in developing siliques up

General Information

EC Number General Information Comment Organism
6.4.1.2 malfunction transfer DNA insertional alleles that completely eliminate the accumulation of subunit BCCP2 have no perceptible effect on plant growth, development, and fatty acid accumulation. In contrast, transfer DNA insertional null allele of the CAC1A gene for subunit BCCP1 is embryo lethal and deleteriously affects pollen development and germination. Reducing BCCP1 accumulation to 35% of wild type levels, decreases fatty acid accumulation and severely affects normal vegetative plant growth Arabidopsis thaliana
6.4.1.2 metabolism ACCase is a key enzyme for de novo fatty acid biosynthesis Arabidopsis thaliana
6.4.1.2 physiological function ACCase is essential for plant seed development Arabidopsis thaliana