Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Li, A.H.; Na, B.K.; Ahn, S.K.; Cho, S.H.; Pak, J.H.; Park, Y.K.; Kim, T.S.
    Functional expression and characterization of a cytosolic copper/zinc-superoxide dismutase of Spirometra erinacei (2010), Parasitol. Res., 106, 627-635.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.15.1.1 gene SeCuZnSOD, DNA and amino acid sequence determination and analysis, genomic organization, sequence alignment and phylogenetic analysis, quantitative RT-PCR expression analysis, recombinant expression as GST-tagged enzyme in Escherichia coli Spirometra erinaceieuropaei

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.15.1.1 H2O2
-
 Spirometra erinaceieuropaei
1.15.1.1 KCN
-
 Spirometra erinaceieuropaei
1.15.1.1 additional information no inhibition by NaN3 Spirometra erinaceieuropaei

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.15.1.1 cytosol
-
 Spirometra erinaceieuropaei 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.15.1.1 Cu2+ a CuZn-superoxide dismutase Spirometra erinaceieuropaei
1.15.1.1 Zn2+ a CuZn-superoxide dismutase Spirometra erinaceieuropaei

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.15.1.1 15800
-
 2 * 42000, recombinant GST-tagged SeCuZnSOD, SDS-PAGE, 2 * 15800, untagged enzyme, SDS-PAGE Spirometra erinaceieuropaei
1.15.1.1 30000
-
 untagged enzyme, gel filtration Spirometra erinaceieuropaei
1.15.1.1 42000
-
 2 * 42000, recombinant GST-tagged SeCuZnSOD, SDS-PAGE, 2 * 15800, untagged enzyme, SDS-PAGE Spirometra erinaceieuropaei

Organism

EC Number Organism UniProt Comment Textmining
1.15.1.1 Spirometra erinaceieuropaei Q6B7T0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.15.1.1 recombinant GST-tagged SeCuZnSOD from Escherichia coli by glutathione affinity chromatography Spirometra erinaceieuropaei

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.15.1.1 larva
-
 Spirometra erinaceieuropaei
-
1.15.1.1 additional information constant expression in plerocercoid larvae and adult worms Spirometra erinaceieuropaei
-

Subunits

EC Number Subunits Comment Organism
1.15.1.1 homodimer 2 * 42000, recombinant GST-tagged SeCuZnSOD, SDS-PAGE, 2 * 15800, untagged enzyme, SDS-PAGE Spirometra erinaceieuropaei

Synonyms

EC Number Synonyms Comment Organism
1.15.1.1 copper/zinc-superoxide dismutase
-
 Spirometra erinaceieuropaei
1.15.1.1 CuZn-SOD
-
 Spirometra erinaceieuropaei

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.15.1.1 8
-
 broad pH optimum Spirometra erinaceieuropaei

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.15.1.1 7 9.5
-
 Spirometra erinaceieuropaei

Expression

EC Number Organism Comment Expression
1.15.1.1 Spirometra erinaceieuropaei the expression of the enzyme is increased in plerocercoid larvae after treated with paraquat and significantly induced under oxidative stress up

General Information

EC Number General Information Comment Organism
1.15.1.1 physiological function the enzyme may play essential roles for survival of the parasite not only by protecting itself from endogenous oxidative stress, but also by detoxifying oxidative killing of the parasite by host immune effector cells Spirometra erinaceieuropaei