BRENDA - Enzyme Database show

In vivo therapy of myocardial infarction with mesenchymal stem cells modified with prostaglandin I synthase gene improves cardiac performance in mice

Lian, W.S.; Cheng, W.T.; Cheng, C.C.; Hsiao, F.S.; Chen, J.J.; Cheng, C.F.; Wu, S.C.; Life Sci. 88, 455-464 (2011)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
5.3.99.4
expressed in Mus musculus mesenchymal stem cells
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.4
Prostaglandin H2
Homo sapiens
-
Prostaglandin I2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.4
Homo sapiens
Q16647
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
716080
Homo sapiens
Prostaglandin I2
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
5.3.99.4
expressed in Mus musculus mesenchymal stem cells
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.4
Prostaglandin H2
Homo sapiens
-
Prostaglandin I2
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
716080
Homo sapiens
Prostaglandin I2
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
5.3.99.4
physiological function
PGIS over-expressed mesenchymal stem cells are more resistant to free radical stress-induced apoptosis, secrete paracrine factors to enhance immunemodulation and, thus, provide cardiac protection
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.3.99.4
physiological function
PGIS over-expressed mesenchymal stem cells are more resistant to free radical stress-induced apoptosis, secrete paracrine factors to enhance immunemodulation and, thus, provide cardiac protection
Homo sapiens