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Literature summary extracted from

  • Moiseyev, G.; Takahashi, Y.; Chen, Y.; Kim, S.; Ma, J.X.
    RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species (2008), J. Biol. Chem., 283, 8110-8117.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.64 expressed in Escherichia coli and in 293A-LRAT cells Gallus gallus
3.1.1.64 expressed in Escherichia coli and in 293A-LRAT cells Homo sapiens
3.1.1.64 expressed in Escherichia coli and in 293A-LRAT cells Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.64 apo-cellular retinol-binding protein type 1
-
 Bos taurus
3.1.1.64 apo-cellular retinol-binding protein type 1
-
 Gallus gallus
3.1.1.64 apo-cellular retinol-binding protein type 1
-
 Homo sapiens
3.1.1.64 N-(12-chloro-11-oxododecyl)acetamide
-
 Bos taurus
3.1.1.64 N-(12-chloro-11-oxododecyl)acetamide
-
 Gallus gallus
3.1.1.64 N-(12-chloro-11-oxododecyl)acetamide
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.64 microsome
-
 Gallus gallus
-
-
3.1.1.64 microsome
-
 Homo sapiens
-
-
3.1.1.64 microsome
-
 Bos taurus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.64 60927
-
 x * 60927, calculated from amino acid sequence Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.64 Bos taurus
-
-
-
3.1.1.64 Gallus gallus
-
-
-
3.1.1.64 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.64 DEAE-Sepharose column chromatography Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.64 retinal pigment epithelium
-
 Gallus gallus
-
3.1.1.64 retinal pigment epithelium
-
 Homo sapiens
-
3.1.1.64 retinal pigment epithelium
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.64 all-trans-retinyl ester + H2O direct substrate Gallus gallus 11-cis-retinol + a fatty acid
-
 ?
3.1.1.64 all-trans-retinyl ester + H2O direct substrate Homo sapiens 11-cis-retinol + a fatty acid
-
 ?
3.1.1.64 all-trans-retinyl ester + H2O direct substrate Bos taurus 11-cis-retinol + a fatty acid
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.64 ? x * 60927, calculated from amino acid sequence Gallus gallus

Synonyms

EC Number Synonyms Comment Organism
3.1.1.64 retinol isomerohydrolase
-
 Gallus gallus
3.1.1.64 retinol isomerohydrolase
-
 Homo sapiens
3.1.1.64 retinol isomerohydrolase
-
 Bos taurus
3.1.1.64 Rpe65
-
 Gallus gallus
3.1.1.64 Rpe65
-
 Homo sapiens
3.1.1.64 Rpe65
-
 Bos taurus