BRENDA - Enzyme Database show

RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species

Moiseyev, G.; Takahashi, Y.; Chen, Y.; Kim, S.; Ma, J.X.; J. Biol. Chem. 283, 8110-8117 (2008)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Bos taurus
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Gallus gallus
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Homo sapiens
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Bos taurus
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Gallus gallus
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Homo sapiens
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Bos taurus
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Gallus gallus
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Homo sapiens
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.64
microsome
-
Gallus gallus
-
-
3.1.1.64
microsome
-
Bos taurus
-
-
3.1.1.64
microsome
-
Homo sapiens
-
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.1.64
60927
-
x * 60927, calculated from amino acid sequence
Gallus gallus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.1.64
Bos taurus
-
-
-
3.1.1.64
Gallus gallus
-
-
-
3.1.1.64
Homo sapiens
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
3.1.1.64
DEAE-Sepharose column chromatography
Gallus gallus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.64
retinal pigment epithelium
-
Bos taurus
-
3.1.1.64
retinal pigment epithelium
-
Homo sapiens
-
3.1.1.64
retinal pigment epithelium
-
Gallus gallus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Gallus gallus
11-cis-retinol + a fatty acid
-
-
-
?
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Homo sapiens
11-cis-retinol + a fatty acid
-
-
-
?
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Bos taurus
11-cis-retinol + a fatty acid
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
3.1.1.64
?
x * 60927, calculated from amino acid sequence
Gallus gallus
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Bos taurus
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Gallus gallus
3.1.1.64
expressed in Escherichia coli and in 293A-LRAT cells
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Bos taurus
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Gallus gallus
3.1.1.64
apo-cellular retinol-binding protein type 1
-
Homo sapiens
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Bos taurus
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Gallus gallus
3.1.1.64
N-(12-chloro-11-oxododecyl)acetamide
-
Homo sapiens
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.64
microsome
-
Gallus gallus
-
-
3.1.1.64
microsome
-
Bos taurus
-
-
3.1.1.64
microsome
-
Homo sapiens
-
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.1.64
60927
-
x * 60927, calculated from amino acid sequence
Gallus gallus
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.1.64
DEAE-Sepharose column chromatography
Gallus gallus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.64
retinal pigment epithelium
-
Bos taurus
-
3.1.1.64
retinal pigment epithelium
-
Homo sapiens
-
3.1.1.64
retinal pigment epithelium
-
Gallus gallus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Gallus gallus
11-cis-retinol + a fatty acid
-
-
-
?
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Homo sapiens
11-cis-retinol + a fatty acid
-
-
-
?
3.1.1.64
all-trans-retinyl ester + H2O
direct substrate
715496
Bos taurus
11-cis-retinol + a fatty acid
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
3.1.1.64
?
x * 60927, calculated from amino acid sequence
Gallus gallus