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Literature summary extracted from

  • Djajanegara, I.; Holtzapffel, R.; Finnegan, P.M.; Hoefnagel, M.H.; Berthold, D.A.; Wiskich, J.T.; Day, D.A.
    A single amino acid change in the plant alternative oxidase alters the specificity of organic acid activation (1999), FEBS Lett., 454, 220-224.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.10.3.11 pyruvate
-
 Glycine max
1.10.3.11 pyruvate
-
 Arabidopsis thaliana

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.10.3.11 expressed in Escherichia strain SASX41B Arabidopsis thaliana
1.10.3.11 expressed in Nicotiana tabacum Glycine max

Protein Variants

EC Number Protein Variants Comment Organism
1.10.3.11 C127S the substitution prevents oxidative inactivation of alternative oxidase and renders the protein insensitive to pyruvate activation, the mutated protein is instead activated specifically by succinate Arabidopsis thaliana
1.10.3.11 C99S the substitution prevents oxidative inactivation of alternative oxidase and renders the protein insensitive to pyruvate activation, the mutated protein is instead activated specifically by succinate Glycine max

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.10.3.11 mitochondrion
-
 Glycine max 5739
-
1.10.3.11 mitochondrion
-
 Arabidopsis thaliana 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.11 Arabidopsis thaliana
-
-
-
1.10.3.11 Glycine max
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.11 ubiquinol + O2
-
 Glycine max ubiquinone + H2O
-
 ?
1.10.3.11 ubiquinol + O2
-
 Arabidopsis thaliana ubiquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.10.3.11 alternative oxidase
-
 Glycine max
1.10.3.11 alternative oxidase
-
 Arabidopsis thaliana
1.10.3.11 AOX1a
-
 Arabidopsis thaliana
1.10.3.11 AOX3
-
 Glycine max