EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.64 | additional information | 13,17,21-trimethyldocosa-12,16,20-trien-11-one and 3,7,11-trimethyldodeca-2,6,10-trienoic acid hexadecylamide are potent mRPE65 antagonists that inhibit 11-cis-retinal regeneration | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.64 | membrane | - |
Bos taurus | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.64 | all-trans-retinyl ester + H2O | Bos taurus | - |
11-cis-retinol + a fatty acid | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.64 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.64 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.64 | optic cup | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.64 | all-trans-retinyl ester + H2O | - |
Bos taurus | 11-cis-retinol + a fatty acid | - |
? | |
3.1.1.64 | all-trans-retinyl palmitate + H2O | - |
Bos taurus | 11-cis-retinol + palmitate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.64 | Rpe65 | - |
Bos taurus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.1.1.64 | physiological function | RPE65 is essential for the operation of the visual cycle. RPE65 is also on the rate-limiting pathway to fluorophore A2E (lipofuscin) formation | Bos taurus |