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Literature summary extracted from

  • Oh, S.K.; Baek, K.H.; Seong, E.S.; Joung, Y.H.; Choi, G.J.; Park, J.M.; Cho, H.S.; Kim, E.A.; Lee, S.; Choi, D.
    CaMsrB2, pepper methionine sulfoxide reductase B2, is a novel defense regulator against oxidative stress and pathogen attack (2010), Plant Physiol., 154, 245-261.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.4.12 expressed in Escherichia coli BL21(DE3) cells Capsicum annuum

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.12 Capsicum annuum B7S5L1 ECW-30R
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.4.12
-
 Capsicum annuum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.12 flower
-
 Capsicum annuum
-
1.8.4.12 leaf
-
 Capsicum annuum
-
1.8.4.12 root
-
 Capsicum annuum
-
1.8.4.12 stem
-
 Capsicum annuum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.12 dabsyl-L-methionine (R)-sulfoxide + thioredoxin
-
 Capsicum annuum dabsyl-L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.12 methionine sulfoxide reductase B2
-
 Capsicum annuum
1.8.4.12 MsrB2
-
 Capsicum annuum

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.4.12 thioredoxin
-
 Capsicum annuum

Expression

EC Number Organism Comment Expression
1.8.4.12 Capsicum annuum MsrB2 is down-regulated upon inoculation with either incompatible or compatible pathogens. The expression of MsrB2 is suppressed by treatment with 0.1 mM methyl jasmonate, 5 mM salicylic acid, and 5 mM ethephone down

General Information

EC Number General Information Comment Organism
1.8.4.12 malfunction loss-of-function studies of MsrB2 using virus-induced gene silencing in pepper plants (cultivar Early Calwonder-30R) result in accelerated cell death from an incompatible bacterial pathogen, Xanthomonas axonopodis pv vesicatoria race 1, and enhanced susceptibility to a compatible bacterial pathogen, virulent Xanthomonas axonopodis pv vesicatoria race 3. Suppression of CaMsrB2 increased the production of reactive oxygen species, which in turn results in the acceleration of cell death via accumulation of reactive oxygen species Capsicum annuum
1.8.4.12 physiological function MsrB2 is a defense regulator against oxidative stress and pathogen attack, MsrB2 causes enhanced resistance to Phytophthora capsici and Phytophthora infestans Capsicum annuum