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Literature summary extracted from

  • Prosser, I.M.; Adams, R.J.; Beale, M.H.; Hawkins, N.D.; Phillips, A.L.; Pickett, J.A.; Field, L.M.
    Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene (2006), Phytochemistry, 67, 1564-1571.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.67 expression in Escherichia coli Mentha x piperita

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.3.67 0.0019
-
 (2E,6E)-farnesyl diphosphate pH 7.2, 27°C Mentha x piperita

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.67 (2E,6E)-farnesyl diphosphate Mentha x piperita
-
 cis-muurola-3,5-diene + diphosphate main products cis-muurola-3,5-diene at 45% and cis-muurola-4(14),5-diene at 43%, minor products gamma-cadinene at 7% and alpha-cadinene at 5% ?
4.2.3.67 (2E,6E)-farnesyl diphosphate Mentha x piperita
-
 cis-muurola-4(14),5-diene + diphosphate main products cis-muurola-3,5-diene at 45% and cis-muurola-4(14),5-diene at 43%, minor products gamma-cadinene at 7% and alpha-cadinene at 5% ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.67 Mentha x piperita Q5W283
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.67 (2E,6E)-farnesyl diphosphate
-
 Mentha x piperita cis-muurola-3,5-diene + diphosphate main products cis-muurola-3,5-diene at 45% and cis-muurola-4(14),5-diene at 43%, minor products gamma-cadinene at 7% and alpha-cadinene at 5% ?
4.2.3.67 (2E,6E)-farnesyl diphosphate
-
 Mentha x piperita cis-muurola-4(14),5-diene + diphosphate main products cis-muurola-3,5-diene at 45% and cis-muurola-4(14),5-diene at 43%, minor products gamma-cadinene at 7% and alpha-cadinene at 5% ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.67 MxpSS1
-
 Mentha x piperita

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2.3.67 0.18
-
 (2E,6E)-farnesyl diphosphate pH 7.2, 27°C Mentha x piperita