EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.9 | auranofin | - |
Haemonchus contortus | |
1.8.1.9 | curcumin | - |
Haemonchus contortus | |
1.8.1.9 | theaflavin | - |
Haemonchus contortus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.8.1.9 | cytoplasm | isoform TrxR1 | Haemonchus contortus | 5737 | - |
1.8.1.9 | mitochondrion | isoform TrxR2 | Haemonchus contortus | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.9 | selenium | TrxR1 contains a selenocysteine in the active site (Gly-Cys-SeCys-Gly) | Haemonchus contortus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.9 | Haemonchus contortus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+ | - |
Haemonchus contortus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
1.8.1.9 | additional information | isoform TrxR1 shows broad activity with thioredoxins from Escherichia coli, sheep, and Haemonchus contortus, while isoform TrxR2 has high activity only with the mitochondrial Haemonchus contortus thioredoxin | Haemonchus contortus | ? | - |
? | |
1.8.1.9 | selenite + NADPH + H+ | - |
Haemonchus contortus | ? + NADP+ | - |
? | |
1.8.1.9 | thioredoxin disulfide + NADPH + H+ | - |
Haemonchus contortus | thioredoxin + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.9 | thioredoxin reductase | - |
Haemonchus contortus |
1.8.1.9 | TrxR1 | isoform | Haemonchus contortus |
1.8.1.9 | TrxR2 | isoform | Haemonchus contortus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.9 | FAD | - |
Haemonchus contortus | |
1.8.1.9 | NADPH | - |
Haemonchus contortus |