EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.8.1.9 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.8.1.9 | 54000 | - |
about 54000 Da, SDS-PAGE | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.9 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.1.9 | ammonium sulfate precipitation, DEAE-Sephacel gel filtration, 2',5'-ADP-Sepharose 4B affinity chromatography, and omega-aminohexyl-Sepharose 4B column chromatography | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.1.9 | brain | - |
Rattus norvegicus | - |
1.8.1.9 | heart | - |
Rattus norvegicus | - |
1.8.1.9 | kidney | - |
Rattus norvegicus | - |
1.8.1.9 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+ | - |
Rattus norvegicus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
1.8.1.9 | alloxan + NADPH + H+ | - |
Rattus norvegicus | ? + NADP+ | - |
? | |
1.8.1.9 | selenite + NADPH + H+ | - |
Rattus norvegicus | ? + NADP+ | - |
? | |
1.8.1.9 | thioredoxin disulfide + NADPH + H+ | - |
Rattus norvegicus | thioredoxin + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.9 | thioredoxin reductase | - |
Rattus norvegicus |
1.8.1.9 | TrxR2 | also called TR3 or TRbeta | Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.9 | FAD | - |
Rattus norvegicus | |
1.8.1.9 | NADPH | - |
Rattus norvegicus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.8.1.9 | malfunction | inhibition of mitochondrial thioredoxin reductase leads to oxidation of downstream enzymes such as thioredoxin and peroxiredoxin | Rattus norvegicus |