BRENDA - Enzyme Database

The cmk gene encoding cytidine monophosphate kinase is located in the rpsA operon and is required for normal replication rate in Escherichia coli

Fricke, J.; Neuhard, J.; Kelln, R.A.; Pedersen, S.; J. Bacteriol. 177, 517-523 (1995)

Data extracted from this reference:

Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.4.25
25000
-
SDS-PAGE
Escherichia coli K-12
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.4.25
Escherichia coli K-12
P0A6I0
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.25
ATP + CMP
-
712269
Escherichia coli K-12
ADP + CDP
-
-
-
?
2.7.4.25
ATP + dCMP
-
712269
Escherichia coli K-12
ADP + dCDP
-
-
-
?
2.7.4.25
ATP + UMP
CMP kinase possess a weak UMP kinase activity
712269
Escherichia coli K-12
ADP + UDP
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.7.4.25
ATP
-
Escherichia coli K-12
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.7.4.25
ATP
-
Escherichia coli K-12
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.4.25
25000
-
SDS-PAGE
Escherichia coli K-12
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.25
ATP + CMP
-
712269
Escherichia coli K-12
ADP + CDP
-
-
-
?
2.7.4.25
ATP + dCMP
-
712269
Escherichia coli K-12
ADP + dCDP
-
-
-
?
2.7.4.25
ATP + UMP
CMP kinase possess a weak UMP kinase activity
712269
Escherichia coli K-12
ADP + UDP
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
2.7.4.25
malfunction
in a strain deleted for cmk, the pools of CMP and dCMP are elevated approximately 30fold
Escherichia coli K-12
2.7.4.25
physiological function
the cmk gene is required for normal replication rate in Escherichia coli
Escherichia coli K-12
General Information (protein specific)
EC Number
General Information
Commentary
Organism
2.7.4.25
malfunction
in a strain deleted for cmk, the pools of CMP and dCMP are elevated approximately 30fold
Escherichia coli K-12
2.7.4.25
physiological function
the cmk gene is required for normal replication rate in Escherichia coli
Escherichia coli K-12