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Literature summary extracted from
- Transgenic mice overexpressing methionine sulfoxide reductase A: characterization of embryonic fibroblasts (2010), Free Radic. Biol. Med., 49, 641-648.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.8.4.11 | cytosol | - |
Mus musculus | 5829 | - |
| 1.8.4.11 | mitochondrion | - |
Mus musculus | 5739 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.8.4.11 | 25000 | - |
SDS-PAGE | Mus musculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.4.11 | Mus musculus | Q9D6Y7 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.4.11 | liver | - |
Mus musculus | - |
| 1.8.4.11 | MEF cell | nontransgenic embryonic fibroblasts lack MsrA | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.4.11 | L-methionine (S)-sulfoxide + 2 dithiothreitol | - |
Mus musculus | L-methionine + dithiothreitol disulfide + H2O | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.4.11 | methionine sulfoxide reductase A | - |
Mus musculus |
| 1.8.4.11 | MsrA | - |
Mus musculus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.4.11 | thioredoxin | - |
Mus musculus | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.8.4.11 | physiological function | overexpression of MsrA does not protect MEF cells from oxidative stress | Mus musculus |
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Release 2023.1 (January 2023)
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