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Literature summary extracted from

  • Beattie, P.; Tan, K.; Bourne, R.M.; Leach, D.; Rich, P.R.; Ward, F.B.
    Cloning and sequencing of four structural genes for the Na+-translocating NADH-ubiquinone oxidoreductase of Vibrio alginolyticus (1994), FEBS Lett., 356, 333-338.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.1.1 2-n-heptyl-4-hydroxyquinoline N-oxide
-
 Vibrio alginolyticus
7.2.1.1 Ag+
-
 Vibrio alginolyticus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.1.1 membrane
-
 Vibrio alginolyticus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.2.1.1 22602
-
 1 * 48622 + 1 * 46809 + 1 * 27672 + 1 * 22602, subunits NqrA, NqrB, NqrC and NqrD, calculated from amino acid sequence Vibrio alginolyticus
7.2.1.1 27672
-
 1 * 48622 + 1 * 46809 + 1 * 27672 + 1 * 22602, subunits NqrA, NqrB, NqrC and NqrD, calculated from amino acid sequence Vibrio alginolyticus
7.2.1.1 46809
-
 1 * 48622 + 1 * 46809 + 1 * 27672 + 1 * 22602, subunits NqrA, NqrB, NqrC and NqrD, calculated from amino acid sequence Vibrio alginolyticus
7.2.1.1 48622
-
 1 * 48622 + 1 * 46809 + 1 * 27672 + 1 * 22602, subunits NqrA, NqrB, NqrC and NqrD, calculated from amino acid sequence Vibrio alginolyticus
7.2.1.1 254000
-
 gel filtration Vibrio alginolyticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.1.1 deamino-NADH + H+ + ubiquinone + n Na+/in Vibrio alginolyticus
-
 deamino-NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 deamino-NADH + H+ + ubiquinone + n Na+/in Vibrio alginolyticus NCIMB 11038
-
 deamino-NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 NADH + H+ + ubiquinone + n Na+/in Vibrio alginolyticus
-
 NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 NADH + H+ + ubiquinone + n Na+/in Vibrio alginolyticus NCIMB 11038
-
 NAD+ + ubiquinol + n Na+/out
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.1.1 Vibrio alginolyticus
-
-
-
7.2.1.1 Vibrio alginolyticus NCIMB 11038
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.2.1.1 partially purified by DEAE Sepharose column chromatography and preparative gel electrophoresis Vibrio alginolyticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.1.1 deamino-NADH + H+ + ubiquinone + n Na+/in
-
 Vibrio alginolyticus deamino-NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 deamino-NADH + H+ + ubiquinone + n Na+/in
-
 Vibrio alginolyticus NCIMB 11038 deamino-NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 NADH + H+ + ubiquinone + n Na+/in
-
 Vibrio alginolyticus NAD+ + ubiquinol + n Na+/out
-
 ?
7.2.1.1 NADH + H+ + ubiquinone + n Na+/in
-
 Vibrio alginolyticus NCIMB 11038 NAD+ + ubiquinol + n Na+/out
-
 ?

Subunits

EC Number Subunits Comment Organism
7.2.1.1 heterotetramer 1 * 48622 + 1 * 46809 + 1 * 27672 + 1 * 22602, subunits NqrA, NqrB, NqrC and NqrD, calculated from amino acid sequence Vibrio alginolyticus

Synonyms

EC Number Synonyms Comment Organism
7.2.1.1 Na+-translocating NADH-ubiquinone oxidoreductase
-
 Vibrio alginolyticus
7.2.1.1 NaΒ’-dependent NADH-ubiquinone oxidoreductase
-
 Vibrio alginolyticus
7.2.1.1 NqrA subunit Vibrio alginolyticus
7.2.1.1 NqrB subunit Vibrio alginolyticus
7.2.1.1 NqrC subunit Vibrio alginolyticus
7.2.1.1 NqrD subunit Vibrio alginolyticus

Cofactor

EC Number Cofactor Comment Organism Structure
7.2.1.1 FAD
-
 Vibrio alginolyticus
7.2.1.1 FMN
-
 Vibrio alginolyticus
7.2.1.1 NADH
-
 Vibrio alginolyticus
7.2.1.1 [2Fe-2S]-center
-
 Vibrio alginolyticus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
7.2.1.1 Vibrio alginolyticus subunit NqrC, calculated from amino acid sequence
-
 4.9
7.2.1.1 Vibrio alginolyticus subunit NqrA, calculated from amino acid sequence
-
 5.6
7.2.1.1 Vibrio alginolyticus subunit NqrB, calculated from amino acid sequence
-
 9.1
7.2.1.1 Vibrio alginolyticus subunit NqrD, calculated from amino acid sequence
-
 9.3