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Literature summary extracted from

  • Wenzl, M.V.; Woelkart, G.; Stessel, H.; Beretta, M.; Schmidt, K.; Mayer, B.
    Different effects of ascorbate deprivation and classical vascular nitrate tolerance on aldehyde dehydrogenase-catalysed bioactivation of nitroglycerin (2009), Br. J. Pharmacol., 156, 1248-1255.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 Chloral hydrate
-
 Cavia porcellus
1.2.1.3 daidzin
-
 Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 mitochondrion
-
 Cavia porcellus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 aorta
-
 Cavia porcellus
-

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 ALDH2
-
 Cavia porcellus

General Information

EC Number General Information Comment Organism
1.2.1.3 malfunction vascular tolerance to nitroglycerin may be caused by impaired nitroglycerin bioactivation due to inactivation of mitochondrial aldehyde dehydrogenase ALDH2 Cavia porcellus