EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.6.2.2 | (17beta)-N-([trans-4-[(6-amino-9H-purin-9-yl)methyl]cyclohexyl]methyl)-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 99% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[(2E)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 72% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[(2Z)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 86% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[4-(6-amino-9H-purin-9-yl)but-2-yn-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 61% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[4-(6-amino-9H-purin-9-yl)butyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 78% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[4-[(6-amino-9H-purin-9-yl)methyl]benzyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 98% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | (17beta)-N-[6-(6-amino-9H-purin-9-yl)hexyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 111% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
7.6.2.2 | progesterone | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.6.2.2 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.6.2.2 | K-562/R7 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.6.2.2 | ATP + H2O + daunorubicin/in | - |
Homo sapiens | ADP + phosphate + daunorubicin/out | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.6.2.2 | ABCB1 | - |
Homo sapiens |
7.6.2.2 | P-glycoprotein | - |
Homo sapiens |